{"id":9273,"date":"2022-06-15T06:11:04","date_gmt":"2022-06-15T06:11:04","guid":{"rendered":"https:\/\/www.booksofall.com\/in\/?post_type=product&#038;p=9273"},"modified":"2022-06-15T06:11:20","modified_gmt":"2022-06-15T06:11:20","slug":"fake-drugs-the-global-industry-putting-your-life-at-risk","status":"publish","type":"product","link":"https:\/\/www.booksofall.com\/in\/fake-drugs-the-global-industry-putting-your-life-at-risk\/","title":{"rendered":"Fake drugs: the global industry putting your life at risk"},"content":{"rendered":"<h4 id=\"standfirst\" class=\"article__standfirst\">The manufacture and distribution of medicines is a global industry, tainted by fake and substandard products. Not only might these\u00a0drugs\u00a0not work as expected, but some are even contributing to antimicrobial resistance. So, what\u2019s in your medicine cabinet?<\/h4>\n<div class=\"paragraph paragraph--text\">\n<p>In late 2012, 60 people died in two cities in Pakistan after drinking cough syrup to get high. Syrups from two separate manufacturers were involved. It was found that both were using an active ingredient \u2013 dextromethorphan, a synthetic morphine-like compound \u2013 imported from the same manufacturer in India. Indian drug authorities put a halt to production while they investigated.<\/p>\n<p>Tests in Pakistan revealed that the medicines seemed to contain the correct amount of active ingredient. But further tests revealed something that was not supposed to be there. Levomethorphan, a chemical five times stronger than morphine, was the contaminant that had caused the deaths.<\/p>\n<\/div>\n<div class=\"paragraph paragraph--text\">\n<p>In September 2013, 44 children in Paraguay were admitted to hospital with breathing difficulties. It turned out the children had all been given a locally made cough medicine. Investigators went to the factory and found import records for the dextromethorphan it contained. When they checked the World Health Organization\u2019s database of substandard and falsified medical products, they found that this came from the same batch that had caused the deaths in Pakistan.<\/p>\n<p>Doctors in Paraguay were able to administer an antidote and save the children. A\u00a0<a href=\"http:\/\/www.who.int\/medicines\/publications\/drugalerts\/en\/\">WHO alert\u00a0<\/a>went out listing the batches from the Indian factory that might be contaminated. By then the ingredient had been transported to multiple countries in Europe, north Africa, the Middle East and Latin America. It had already been made into cough medicines in Colombia and Peru, but these were recalled before they could reach patients. The batch that went to the Middle East could not be traced.<\/p>\n<h4>Reference:<\/h4>\n<ul>\n<li><a href=\"https:\/\/amr-review.org\/sites\/default\/files\/ElizabethPisaniMedicinesQualitypaper.pdf\">Antimicrobial resistance: What does medicine quality have to do with it?<\/a>\u00a0A 2015 paper by Elizabeth Pisani for the Review on Antimicrobial Resistance that reviews what is known about the contribution of poor quality medicines to antimicrobial resistance.<\/li>\n<li>The WHO\u00a0<a href=\"http:\/\/www.who.int\/medicines\/regulation\/ssffc\/publications\/gsms-report-sf\/en\/\">Global Surveillance and Monitoring System<\/a>\u00a0for substandard and falsified medical products.<\/li>\n<li>The Center For Disease Dynamics, Economics &amp; Policy\u2019s report:\u00a0<a href=\"https:\/\/cddep.org\/publications\/state_worlds_antibiotics_2015\/\">The state of the world\u2019s antibiotics, 2015<\/a>.<\/li>\n<li>A 2016 paper by Paul\u00a0Newton and colleagues on\u00a0<a href=\"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14787210.2016.1187560\">a link between poor quality antimalarials and malaria drug resistance<\/a>.<\/li>\n<li>A 2013\u00a0Wall Street Journal\u00a0piece on how\u00a0<a href=\"https:\/\/www.wsj.com\/articles\/SB10001424127887324474004578444942841728204\">fake drugs are undermining Africa\u2019s battle against malaria<\/a>.<\/li>\n<li>A 2016 paper co-authrored by Ramanan Laxminarayan on\u00a0<a href=\"https:\/\/journals.plos.org\/plosmedicine\/article?id=10.1371\/journal.pmed.1001974\">antibiotic resistance in India<\/a>.<\/li>\n<li>Posts on the\u00a0<a href=\"http:\/\/afludiary.blogspot.com\/\">Avian Flu Diary blog<\/a>\u00a0offer a good timeline of research results on topics related to resistance, such as\u00a0<a href=\"http:\/\/afludiary.blogspot.com\/search?q=NDM-1\">NDM-1<\/a>.<\/li>\n<\/ul>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p><iframe style=\"width: 100%; height: 750px; border: none;\" src=\"https:\/\/online.visual-paradigm.com\/share\/book\/fake-drugs-the-global-industry-putting-your-life-at-risk-zl4vi9kwl?enforceShowPromotionBar=true\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n","protected":false},"featured_media":9283,"template":"","meta":{"_yoast_wpseo_title":"","_yoast_wpseo_metadesc":"The best strategy to save money for your marketing campaign. 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